Given the fact that astrocytes are capable of modulating biologic properties and behavior of cancer cells,12 we hypothesized that they could induce formation of brain metastases through suppression of KISS1 expression among BrCa cells, entering into the brain

As a result, defining the systems and elements that control Treg cell balance/plasticity may donate to our knowledge of the systems mixed up in immune deregulation seen in chronic inflammation and autoimmunity also to the look of regulatory T cell-based therapies